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Chelation Therapy Article

Chelation Therapy

Chelation Therapy

By:
Dr. Asmita Chaturvedi; M.D.(Internal Medicine)
Dr. Deepak Chaturvedi; M.D. (Internal Medicine)




Chelation Therapy

Heavy metals are ubiquitous and have the potential to get access inside our body through Food, Water, Air, Medicines, Supplements, Implants and other means. Our body is equipped to handle (maintain and excrete) limited amount of metals entered in the body. Any amount more than this gets accumulated and causes widespread “Inflammation” and “Destruction” within the body.

When the heavy metals gets accumulated and deposited in vital organs, the following systemic complications may occur.

  • Brain : Dementia, Mood Disorders, Autism, Movement disorders.
  • Blood Vessels: Atherosclerosis, Blockages, Peripheral Vascular Diseases (PVD)
  • Heart: Cardiomyopathy, IHD, Heart Failure
  • Kidneys: Acute Renal Shut down, CKD, Nephropathy
  • Liver: Hepatitis, Cirrhosis
  • Lungs: Fibrosis, Atelectasis, COPD, Bronchial Asthma
  • Adipocytes: Metabolic Syndrome, Insulin Resistance
  • Pancreas: Diabetes Mellitus
  • Muscles: Myopathy, Insulin Resistance
  • Bones: Osteoporosis, Osteomalacia
  • Eyes: Cataract, Retinopathy
  • Ears: Hearing Loss, Vertigo
  • Nose: Anosmia, Parosmia
  • Blood Cells: Anaemia

Chelation Therapy

Heavy Metal over-exposure and/or toxicity is associated with:

  • Malignancies
  • Skin, Hairs and Nails Conditions
  • Ischemic Heart Disease
  • Premature Aging
  • Unexplained Disorders
  • Chronic Fatigue Syndrome

Common Heavy Metals over-exposure and/or Toxicities encountered in Practice:

  • Lead
  • Iron
  • Aluminium
  • Arsenic
  • Mercury
  • Cadmium
  • Copper
  • Calcium

Common Sources of Heavy Metals:

  • Lead : Plumbing materials, Ground water, Soil, Gasoline vapors, Wall Paints, Batteries
  • Iron: Cooking wares, Nutritional Supplements, Plumbing materials, Repeated Blood Transfusions
  • Aluminium: Cooking wares, Toothpaste, Deodorants, Perfumes, Implants, Vaccines(?)
  • Arsenic: Soil, Ground water, Homeopathic Medicines, Ayurvedic supplements, Herbal supplements
  • Cadmium : Batteries, Soil, Ground water
  • Copper: Cooking wares, Utensils, Supplements, Implants
  • Calcium: Dietaty, Supplements

Chelation Therapy

Chelation Therapy , if given judiciously and in a supervised manner can provide relief to the Heavy metals over-exposure and/or toxicities and provide Systemic and Subjective improvement in the health conditions associated with such over-exposure and toxicities.

Commonly used medicines for Chelation therapy are Disodium EDTA, Desferrioxamine and DMSA.





Heavy Metals and Heart:

The Heavy Metals (Mainly Calcium, which is an alkaline Earth Metal) form the base of the Atheromatous Plaques in the coronary circulation (blood vessels of heart) and other blood vessels of the body. The plaques deposits in the coronary circulation lead to the blockages and subsequently may lead to the Heart Attack (Myocardial Infarction, Coronary Artery Disease, Ischemic Heart Disease). The blockages in blood vessels of other organs lead to the damage of the respective organs.

For Coronary Artery Disease (The Heart Blockages), there are conventional treatment strategies as Coronary Angioplasty and Coronary Artery Bypass Grafting (CABG) with the routine medical management including antiplatelets, Lipid lowering agents with/without anticoagulants.

For the patients, who are either not fit to undergo the conventional treatments or the ones who have not achieved the relief from the symptoms or the ones who are waiting for such procedures, there are two options available (Singly or in combinations):

  • 1. EECP (Enhanced External Counter Pulsation)
  • 2. Chelation

Chelation Therapy in Cardivascular Diseases (Blockages):

1. Also known as “ACT” (Arterial Clearance Therapy) or “Bio Chemical Angioplasty” (BCA). Both these terms are not absolute. These terms are used more as the Medical Slangs.

Chelation Therapy

2. Suitable for the patients who are:

  • Not fit to undergo Coronary Angioplasty or CABG (Bypass Surgery)
  • Still having symptoms after undergoing the conventional treatments like PTCA and/or CABG.
  • Not having the blockages significant enough to call for PTCA or CABG but the symptoms are there.
  • Willing to use Chelation/EECP as the bridge therapy while waiting to undergo PTCA/CABG.

3. Investigations to be done prior to initiation of Chelation Therapy (ACT/BCA):

  • Kidney Function Test
  • Liver Function Test
  • HbA1c
  • Ionized Calcium
  • Heavy Metals level
  • Complete Haemogram with ESR
  • Serum Iron Studies
  • Serum Vitamin B12, Vitamin D
  • Lipid Profile
  • Resting ECG
  • Stress Test
  • 2-D Echocardiography
  • CT-Coronary Angiography (If possible, for Calcium Scoring)
  • Other investigations as decided by the treating Physician.

4. Which candidates are not ideal for the Chelation Therapy?

  • Kidney Failure (CKD, ARF)
  • Patients on Blood Thinners
  • Grossly uncontrolled Diabetes Mellitus
  • Non Ischemic Dilated Heart
  • Liver Failure
  • Ishaemic Heart Failure (Caution)
  • Acute Left Ventricular Failure
  • Moderate to Severe Osteoporosis
  • Hypoparathyroidism and Hyperparathyroidism

Chelation Therapy

5. How many sessions are required?

  • Depends on case to case.
  • It can go upto 52 sessions over a period of 18-24 months.

6. What is the length of each session?

  • Varies case to case
  • Minimum length of each session is 2 hours.

7. How frequent are the sessions required?

  • Once a week for 12 weeks.
  • Then once in 2 weeks.
  • The frequency can vary from case to case.

Chelation Therapy

8. When can the whole treatment be repeated after completion of one treatment of 52 sessions?

  • It depends on case to case.
  • The treatment can be repeated after a gap of 6 months of completion of the previous treatment of 52 sessions (and as and when basis).

9. What are the usual constituents of the Chelation Therapy?

  • The constitution varies from case to case. It usually comprises of Disodium EDTA, Ascorbic Acid, Magnesium Chloride, Procaine Hydrochloride, Heparin, Potassium Chloride, Sodium Bicarbonate, Pantothenic Acid, Thaimine, Pyridoxine, Cyanocobalamine, NAC in intravenous fluid.

10. Important Instructions:

  • Patient should inform the doctor if he/she is on any supplements (Iron, Calcium, Zinc ETC).
  • Patient should inform the doctor if he/she is on any Ayurvedic/Homeopathic/Herbal/Unani or any other alternative medicines.
  • Patient should come for the chelation therapy after eating some food. The patient should not come empty stomach or fasting for the same.
  • Doctor should monitor the patient for Hypoglycemia, Hypocalcemia, Hypotension, Fluid Overload, Allergy or any other symptoms during the session.